| Title | Computer-assisted adjustment of inspired oxygen concentration improves control of oxygen saturation in newborn infants requiring mechanical ventilation. |
| Author(s) | Yao Sun; Isaac S. Kohane; Ann R. Stark |
| Source | Journal of Pediatrics, Vol. 131, Pages 754-756 |
| Publication Date | Nov. 1997 |
| Abstract | Open-loop computer control of inspired oxygen concentation was evaluated in 16 newborn infants requiring mechanical ventilation. FiO2 and oxygen saturation were compared for 2-hour periods of computer versus routine manual FiO2 adjustment. During computer-assisted FiO2 adjustment, patients spent more time at the target SaO2 and less time with SaO2 less than 90 percent. |